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The show starred Mandy Patinkin as Dr. Jeffrey Geiger, a hot-shot surgeon with emotional issues stemming from the psychiatric condition of his wife (played by Kim Greist), who drowned their infant son. Adam Arkin plays Dr. Aaron Shutt, a world-renowned neurosurgeon and Dr. Geiger's best friend. Thomas Gibson played Dr. Daniel Nyland, a promiscuous ER doctor and trauma surgeon who was later suspended due to him having an affair with a patient's family member and later was injured in a car crash. Dr. Keith Wilkes played by Rocky Carroll, often clashed with Nyland and was known for his back-to-basics and rough demeanor. He was good friends with Peter Berg's character, Dr. Billy Kronk. Kronk was known for his cowboyish demeanor and known to be very cocky, as showed in an episode where he cuts off a man's injured leg with a chainsaw in a scene where Kronk helps out at an accident site. Peter MacNicol, Héctor Elizondo and Alan Rosenberg feature as the hospital's in-house attorney and chief of staff, respectively. Christine Lahti joined in the second season as a talented cardiac surgeon with a chip on her shoulder, vying with Geiger for the chief of surgery position. She was known fighting in a custody battle with her malicious ex-husband and businessman, Tommy Wilmette, played by Ron Silver. Mr. Wilmette did everything he could to get Austin to lose custody of their daughter. He purchased the hospital at the end of Season 2. Dr. Austin is suspened because she and her daughter go AWOL on a trip to New Zealand. Mr. Wilmette was upset because it took him three months to find his ex-wife and daughter. In Season 3, the doctors want Mr. Wilmette to sell the hospital and the doctors would run it. The doctors viewed that Wilmette didn't know how to run a hospital and cut too many costs that involved patient care. Mr. Wilmette later met with Senator Kennedy at the White House to talk about Healthcare Reform. In Season 2, Geiger resigns from Chicago Hope after trying to save Alan Birch from a deadly gunshot wound to his heart.
Geiger adopted Birch's baby daughter. Geiger later rejoins the doctors at the end of Season 5 when he becomes Chairman of the Board and fires half of the doctors. In Season 4, Dr. Shutt became a psychiatrist and temporarily lost his ability to operate after suffering from a brain aneurysm. In Season 6, Shutt returns to Neurosurgery and works alongside Carla Gugino's character, Dr. Gina Simon.[
|Season One||September 18, 1994||May 22, 1995||22|
|Season Two||September 18, 1995||May 20, 1996||23|
|Season Three||September 16, 1996||May 19, 1997||26|
|Season Four||October 1, 1997||May 13, 1998||24|
|Season Five||September 30, 1998||May 19, 1999||24|
|Season Six||September 23, 1999||May 4, 2000||22|
- At a Glance: Additional information about the series
The entire series is available on DVD in the UK only.