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These Ties That Bind is the eighth episode of the fifth season of Grey's Anatomy, and the eighty-sixth episode overall.

Starring: Ellen Pompeo (Meredith), Sandra Oh (Cristina), Katherine Heigl (Izzie), Justin Chambers (Alex), T.R. Knight (George), Chandra Wilson (Miranda), James Pickens, Jr. (Richard), Sara Ramirez (Callie), Eric Dane (Mark), Chyler Leigh (Lexie), Patrick Dempsey (Derek)

Guest Starring: (in credits order) Jeffrey Dean Morgan (Denny), Kevin McKidd (Owen), Melissa George (Sadie), August Schellenberg (Clay Bodoni), Ed Lauter (Timothy Miller), Brandon Scott (Intern Spalding), Mary McDonnell (Dr. Virginia Dixon)

Contents 1 Plot Overview 2 Notes 3 Arc Advancement 3.1 Happenings 3.2 Characters 3.3 Referbacks 4 Trivia 4.1 The Show 4.2 Behind the Scenes 4.3 Allusions and References 4.4 Memorable Moments 5 Quotes

[edit] Plot Overview

[edit] Notes

[edit] Arc Advancement

[edit] Happenings

[edit] Characters

[edit] Referbacks

[edit] Trivia

[edit] The Show

[edit] Behind the Scenes

[edit] Allusions and References

[edit] Memorable Moments

[edit] Quotes