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Grey's Anatomy/The Heart of the Matter

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The Heart of the Matter
Season 4, Episode 4
Airdate October 18, 2007
Production Number 40465
Written by Allan Heinberg
Directed by Randy Zisk
← 4x03
Let the Truth Sting
4x05 →
Haunt You Every Day
Grey's AnatomySeason Four
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The Heart of the Matter is the fourth episode of the fourth season of Grey's Anatomy, and the sixty-fifth episode overall.

Starring: Ellen Pompeo (Meredith), Sandra Oh (Cristina), Katherine Heigl (Izzie), Justin Chambers (Alex), T.R. Knight (George), Chandra Wilson (Miranda), James Pickens, Jr. (Richard), Sara Ramirez (Callie), Eric Dane (Mark), Chyler Leigh (Lexie), Patrick Dempsey (Derek)

Guest Starring: (in credits order) Edward Herrmann (Dr. Norman Shales), Michael McGrady (Stanley Singer), Matt Lanter (Adam Singer), Maggie Siff (Ruthie Sales), Miriam Flynn (Gretchen Bitzer), Camille Winbush (Camille Travis), Ron Melendez (Will), Loretta Devine (Adele Webber), Shelley Robertson (Arlene Travis), Jeremy Rabb (ER Resident), Maile Flanagan (Lab Tech), Tymberlee Chanel (Intern Claire), Gloria Garayua (Intern Graciella), Richard Keith (Intern Mitch), Molly Kidder (Intern Megan), Joy Osmanski (Intern Lucy), Mark Saul (Intern Steve), Winston Story (Intern Leo), Cassandra Braden (Housekeeping Staffer), Nicole Cummins-Rubio (Paramedic)

Contents

Plot Overview

Notes

Arc Advancement

Happenings

Characters

Referbacks

Trivia

The Show

Behind the Scenes

Allusions and References

Memorable Moments

Quotes