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Supergirl/O Brother, Where Art Thou?
| O Brother, Where Art Thou? | |
| Season 4, Episode 15 | |
| Airdate | March 17, 2019 |
| Production Number | T13.21215 |
| Written by | Derek Simon & Nicki Holcomb |
| Directed by | Tawnia McKiernan |
| Stream |  |
| ← 4x14 Stand and Deliver |
4x16 → The House of L |
| Supergirl — Season Four | |
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O Brother, Where Art Thou? is the fifteenth episode of the fourth season of Supergirl, and the eightieth episode overall.
Starring: Melissa Benoist (Kara Zor-El / Kara Danvers / Supergirl), Mehcad Brooks (James Olsen), Chyler Leigh (Alexandra "Alex" Danvers), Katie McGrath (Lena Luthor), Jesse Rath (Querl Dox / Braniac 5), Sam Witwer (Ben Lockwood / Agent Liberty) (credit only), Nicole Maines (Nia Nal / Dreamer), April Parker Jones (Colonel Lauren Haley) (credit only)
and David Harewood (J'onn J'onzz / Martian Manhunter)
Special Guest Star: Jon Cryer (Lex Luthor)
Guest Starring: David Ajala (Manchester Black), Robert Baker (Otis Graves), Azie Tesfai (Kelly Olsen), Andrea Brooks (Eve Teschmacher), William MacDonald (Dr. Kaplan)
Co-Starring: Byron Brisco (Guard #2), Christina Lewall (Trauma Doctor), Lincoln McGowan (Guard), Amos Stern (Guard #3)
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