Season Twenty-Two of Grey's Anatomy premiered on October 9, 2025.
Episodes
| # |
#
|
Title
|
Written By
|
Directed By
|
Airdate
|
Viewers
|
18-49 Rating
|
|
| 449 |
1
|
Only the Strong Survive
|
Meg Marinis
|
Debbie Allen
|
October 9, 2025
|
2.607M
|
0.27%
|
|
| 450 |
2
|
We Built This City
|
Zoanne Clack
|
Kevin McKidd
|
October 16, 2025
|
2.195M
|
0.18%
|
|
| 451 |
3
|
Between Two Lungs
|
Sandra Hamada
|
Debbie Allen
|
October 23, 2025
|
2.162M
|
0.23%
|
|
| 452 |
4
|
Goodbye Horses
|
Jase Miles-Perez
|
Sammi Cannold
|
October 30, 2025
|
2.134M
|
0.24%
|
|
| 453 |
5
|
Sometimes I Feel Like a Motherless Child
|
Jess Righthand
|
Bille Woodruff
|
November 6, 2025
|
2.042M
|
0.17%
|
|
| 454 |
6
|
When I Crash
|
Michelle Lirtzman
|
Phylicia Rashad
|
November 13, 2025
|
1.835M
|
0.13%
|
|
| 455 |
7
|
Skyfall
|
Carol Brown
|
Allison Liddi-Brown
|
January 8, 2026
|
2.035M
|
0.15%
|
|
| 456 |
8
|
Heavy on Me
|
Tameson Duffy
|
Lisa Leone
|
January 15, 2026
|
2.228M
|
0.17%
|
|
| 457 |
9
|
Fortunate Son
|
Julie Wong
|
Kim Raver
|
January 22, 2026
|
2.446M
|
0.18%
|
|
| 458 |
10
|
Strip That Down
|
Min-Woo Park
|
Kevin McKidd
|
January 29, 2026
|
2.435M
|
0.22%
|
|
| 459 |
11
|
(If You Want It) Do It Yourself
|
Scott D. Brown
|
Linda Klein
|
February 26, 2026
|
2.248M
|
0.15%
|
|
| 460 |
12
|
Get Lucky
|
Jess Righthand
|
Chandra Wilson
|
March 5, 2026
|
2.152M
|
0.18%
|
|
| 461 |
13
|
Love the Way You Lie
|
Sophia Arnao
|
Allison Liddi-Brown
|
March 12, 2026
|
2.217M
|
0.22%
|
|
| 462 |
14
|
Wrecking Ball
|
Michelle Lirtzman
|
Kevin McKidd
|
March 19, 2026
|
2.367M
|
0.2%
|
|
| 463 |
15
|
Take Me to the River
|
Jase Miles-Perez
|
Bille Woodruff
|
March 26, 2026
|
2.648M
|
0.2%
|
|
| 464 |
16
|
Feel It Still
|
Sandra Hamada
|
Jake Borelli
|
April 2, 2026
|
2.381M
|
0.19%
|
|
| 465 |
17
|
Through the Fire
|
Julie Wong
|
Linda Klein
|
April 30, 2026
|
2.206M
|
0.17%
|
|
| 466 |
18
|
Bridge Over Troubled Water
|
Meg Marinis
|
Kevin Mckidd
|
May 7, 2026
|
2.688M
|
0.24%
|
|
