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It's the End of the World is the sixteenth episode of the second season of Grey's Anatomy, and the twenty-fifth episode overall.

Starring: Ellen Pompeo (Meredith), Sandra Oh (Cristina), Katherine Heigl (Izzie), Justin Chambers (Alex), T.R. Knight (George), Chandra Wilson (Bailey), James Pickens, Jr. (Richard), Kate Walsh (Addison), Isaiah Washington (Burke), Patrick Dempsey (Derek)

Guest Starring: (in credits order) Christina Ricci (Hannah Davies), Kyle Chandler (Dylan Young), Jillian Armenante (Mindy Carlson), Cress Williams (Tucker Jones), Larry Clarke (Paul), Cathy Lind Hayes (Nurse Debbie), Moe Irvin (Nurse Tyler), Kathleen M. Darcy (Anesthesiologist), John Bishop (James Carlson), Marty Lodge (Dr. Milton), O. Austin Rey (Bomb Squad #1), Jamal Thomas (Larry the Paramedic),

Contents 1 Plot Overview 2 Notes 3 Arc Advancement 3.1 Happenings 3.2 Characters 3.3 Referbacks 4 Trivia 4.1 The Show 4.2 Behind the Scenes 4.3 Allusions and References 4.4 Memorable Moments 5 Quotes 6 Reviews

[edit] Plot Overview

[edit] Notes

[edit] Arc Advancement

[edit] Happenings

[edit] Characters

[edit] Referbacks

[edit] Trivia

[edit] The Show

[edit] Behind the Scenes

[edit] Allusions and References

[edit] Memorable Moments

[edit] Quotes

[edit] Reviews

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